The drug Viagra promotes blood vessel dilation by prolonging signaling through nitric oxide (NO). How does Viagra boost NO?
a. It inhibits guanylyl cyclase in smooth muscle cells.
b. It prevents acetylcholine from binding to its receptors.
c. It stimulates guanylyl cyclase in smooth muscle cells.
d. It blocks the enzyme that degrades cyclic GMP.
e. It binds to acetylcholine receptors on endothelial cells.

Answers

Answer 1

Answer:

The correct answer is option d, that is, it prevents the enzyme, which degrades cyclic GMP.

Explanation:

Oral therapy for erectile dysfunction is Viagra, which is the citrate salt of sildenafil, it works by preventing a specific phosphodiesterase type 5 or PDE5, which is the inhibitor of cGMP. During sexual stimulation, nitrous oxide is released in the corpus cavernosum causing the erection of the penis in males. The nitrous oxide then stimulates the enzyme guanylate cyclase that further makes the concentration of cGMP to elevate, this generates smooth muscle relaxation in the corpus cavernosum and permitting blood the inward flow of blood.

Viagra works by increasing the influence of nitric acid by preventing PDE5, which is accountable for the deprivation of cGMP in the corpus cavernosum. At the time of sexual stimulation, the discharging of nitrous oxide takes place, the viagra inhibits PDE5 causing the levels of cGMP to elevate in the corpus cavernosum leading to smooth muscle relaxation and continuous flow of blood to the corpus cavernosum.


Related Questions

How do bile salts help in digestion? ​

Answers

They dissolve food in the stomach to easily pass through the intestines

PLZ PLZ HELP I AM VERY STUCK ON THIS QUESTION AND HAVE NO IDEA WHAT IT MEANS!!!

The average temperature of Mars has been plotted on this number line.


Moving from the temperature of Mars in the direction of the long arrow, the temperatures become:

• colder
• warmer

Answers

Answer:

They become colder

Explanation:

Hope I helped

Answer:

Colder

Explanation:

drow the typical picture of animal cell​

Answers

Answer:

Hope this helps!

Explanation:

Brainliest please?

Help please I'll give brainlist
The environment limits population growth by changing birth and death rates. Briefly describe how each environmental factor listed below influences population size. Also, identify each environmental factor as a biotic or abiotic factor

Competitors
Disease
Food
Ph level
Prediction
Soil type
Temperature
Water availability

Answers

Answer:

Soil type

Water availability

Ph level

Competitors

Explanation:

srry if this is not correct im not that smart

What form does the radiation that is used to treat cancer take?
SOS
alpha particles
photons
beta particles
neutrons

Answers

Answer:

Photon radiation

A high-energy photon beam is by far the most common form of radiation used for cancer treatment. It is the same type of radiation that is used in x-ray machines, and comes from a radioactive source such as cobalt, cesium, or a machine called a linear accelerator (linac, for short).

The speed of radioactive particles is also an important factor in medical use. Beta particles travel very fast. This, combined with their small size, gives them significant penetrating power. In cancer treatment, for example, beams of beta particles can be created outside the patient's body and directed at tumors.

Answer:

b

Explanation:

In the example, no RNA is made during the process. What would need to occur for lacZ to be expressed in mRNA

Answers

Answer:

In activity 1, lacZ was expressed under the lactose culture evidenced by 2c having the highest b-gal activity. There is a sign of activation in lactose culture since allolactose (inducer) which is an isomer of lactose, binds the repressor protein.

Explanation:

Answer: What my dude rays said trust me he is smart!!! :)

How are molecules moved across the membrane during active transport? A. They slide through the small spaces in the membrane. B. They are moved using transport proteins and pumps. C. They attach themselves to the membrane and are pulled through

ASAP​

Answers

B. They are moved using transport proteins and pumps.

Answer:

B. they are moved using transport protiens and pumps

Explanation:

just took a test on this

Why is it difficult to know the impacts of deep sea mining?
O It has never been tried successfully, so we don't know exactly how it can be done.
Olt is only done in environmentally sensitive areas, where the organisms are being harmed in many ways already, and it is difficult to know the effects of mining.
We know relatively little about deep sea ecosystems, making it harder to assess the impact of mining.
O Most countries have laws against it, so the impacts have not been tested.

Answers

Answer:

I'm pretty sure its...

Explanation:

We know relatively little about deep sea ecosystems, making it harder to assess the impact of mining.

Deep sea mining has never been tried successfully, so we don't know exactly how it can be done so it is difficult to know the impact of deep sea mining.

what is deep sea mining?

The process of extracting and often excavating mineral deposits from the deep seafloor is known as deep-sea mining.

The deep bottom spans around two-thirds of the total seafloor and is found at ocean depths greater than 200 meters.

Deep-sea mining has been shown to affect marine biodiversity and ecosystems, but we still lack the knowledge and resources to safeguard them.

There are considerable gaps in our understanding of the deep sea's biodiversity and ecosystems since it is still understudied and poorly understood.

This makes assessing the possible effects of deep-sea mining and putting in place necessary safeguards to protect the marine ecosystem and the three billion people whose livelihoods rely on marine and coastal biodiversity challenging.

Hence , the correct option is A.

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Which of the following is not a structure of the nervous system? A. The brain B. The heart C. The spinal cord D. Cranial nerves

Answers

Answer:

heart

Explanation:

bc i got it right on plato

sunspots sit on the sun's ____

Answers

Answer:

photosphere

Explanation:

plz mark B R A I N L I E S T

The cytoplasmic extensions that, together with the cell body, provide the main receptive surfaces for neurons are:_______.
a. dendrite.
b. axon.
c. cell body.
d. neuroglia.

Answers

Answer:

Dendrite

Explanation:

Dendrite with cell body are cytoplasmic projections that are present at the begin of neurons and help increase the cell body surface area through their extensions. The cytoplasm of dendrites and that of cell body have the same number of neurons. Dendrite receive electrical impulses from neurons and send those information to the sons.

Can someone smart help me with this ?

Answers

Cellular Respiration

Sand is a ______ because you can see and identify the individual particles throughout.

Answers

Answer:

Heterogeneous

Explanation:

Sand may appear homogeneous from a distance but it is heterogeneous.

The Chatham Island robin is a small endangered bird found in scrub forests off the coast of New Zealand. The robin is preyed upon by introduced species such as cats and rats. In 1980, the population decreased to only 5 individuals and every individual today is a descendant of a single female. Which of the following is best illustrated in the decline of the Chatham Island robins?
1. Carrying capacity
2. Population bottleneck
3, Population overshoot
4. Type I survivorship

Answers

Answer: 2. Population bottleneck

Explanation:

A Population bottleneck is a term used to refer to an event that causes the population of a species to reduce in very large numbers. Such an event can be environmental disasters like famine, the overhunting of a species or the destruction of its habitat.

In the case of the Cha-tham Island Robin, the bottleneck event must have been the introduction of cats and rats which then went on to hunt the birds to near extinction.

Which of the following non-renewable sources of energy has the smallest amount of
Fuel left on Earth?

Answers

Answer:

just so I can see the question dont mind this

Answer:

You didn’t put any options if you say the options i will answer.

Explanation:

Energy is either released or transferred as molecules are broken down into smaller molecules True or false

Answers

False. Energy is only released when chemical bonds are formed.

Help please thank you so much

Answers

Answer: A!
Hope it helps :D

which species of protozoan causes the african sleeping sickness?
A . plasmodium vivax
B . entamoeba histolytica
C . balantidium coli
D . trypanosoma brucei gambiense

Answers

The correct answer is D.

this is a protozoan that uses the tse-tse fly as a vector and causes african sleeping sickness. This parasite is usually found in csf

A partial DNA sequence for normal hemoglobin and a partial DNA sequence for sickle-cell anemia are shown below. G-G-A-C-T-T-C-T-T Normal hemoglobin G-G-A-C-A-T-C-T-T Sickle-cell anemia Based on the DNA sequences, sickle-cell anemia is caused by A. a sex-linked trait. B. a dominant nucleotide. C. a mutation in the genetic code. D. an incomplete separation of chromosomes.

Answers

Answer:

C. a mutation in the genetic code.

Explanation:

A mutation refers to any change or alteration to the nucleotide sequence of a gene caused by mutagen or mistakes during replication. Depending on the manner of occurrence, mutation can be of different types. In this question, partial DNA sequence for normal hemoglobin is given as: G-G-A-C-T-T-C-T-T while the partial DNA sequence for sickle cell anaemia is given as: G-G-A-C-A-T-C-T-T.

From careful observation of the two two DNA sequences above, it can be realized that a SUBSTITUTION MUTATION from T to A has occurred in the sequence of sickle cell. Note that substitution mutation is the replacement of one base by another in a sequence.

What is the second most abundant element on earth and seems to be very important in biological processes such as oxygen transportation in the body and cellular respiration

Answers

Answer:

iron

Explanation:

Cellular respiration may be defined as the group of metabolic processes as well as reactions which occurs in the cells of the organisms that converts the chemical energy from the oxygen molecules or from nutrients into ATP or adenosine triphosphate and then releases the waste products. Thus it breaks the glucose and produces the ATP. Iron is an important element which are used in many important biological processes in the body like the cellular respiration and oxygen transportation.

Tim has long eyelashes (dominant) and Karen has short eyelashes (recessive). Which statement is true?
O You know Tim's genotype and phenotype.
O You only know Tim & Karen's genotype.
O You know Karen's genotype and phenotype. O You know both Tim & Karen's genotype and phenotype.​

Answers

O You know Karen's genotype and phenotype.  

because short eyelashes is a recessive gene and that means it's present in two copies

During photosynthesis, plants capture light energy and form carbon-containing molecules, such as glucose. Which is not a use for glucose

Answers

Answer:

During photosynthesis, plants capture light energy from the Sun to break weak bonds in reactants, such as carbon dioxide and water, and form carbon containing molecules, such as glucose. The carbon containing molecules can then be used:

✓ to assemble larger molecules, such as DNA, proteins, and fats.

Explanation:

At L. T. Manufacturing, a team was formed to tackle recent issues with the timely shipping of products Members of the team come from different departments including production, design distribution, and marketingWhich of the following terms can best describe the team?

Answers

Answer:

Cross-functional group

Explanation:

Cross-functional group is a group in which members come from a different department of a company with a specific type of skill together with a common goal.

For instance, in this company, various members of a group come together from different departments including production, design distribution, and marketing to tackle a problem.

Which of the following has the greatest effect
on soil's capacity to retain water?
A Soil color
B Soil particle size
C Soil texture
D Soil fragrance

Answers

The water-holding capacity of a soil is the  the amount of water that a given soil can hold for plants to utilize

The soil particle size has the greatest effect on soil's capacity to retain water.

Soil particle size and organic matter (the soil's composition) are main determinants of water-holding capacity of a soil. Smaller particles (silt and clay) have a bigger surface area than larger sand particles, allowing the soil to hold more water.

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List two "firsts" in the animal kingdom that a sponge can claim

Answers

Answer:

Two first the sponge can claim are

1. reproduce sexually

2. combine sperm and egg

The Sponge belongs to the Phylum Porifera of the Animal Kingdom. These are the first organisms in the animal kingdom who can reproduce by sexual reproduction and shows male and female gamete formation.  

What are Sponges?

The Sponges are the members of the phylum Porifera of the Animal kingdom. Sponges are the basal animal clade and the sister of the diploblasts. These are multicellular organisms whose bodies are fully-covered with the pores and channels that allows water to circulate through them. A layer consisting of jelly-like substance is sandwiched between two thin layers of cells in the body cavity of these organisms.

Sponges are the first organisms in the animal kingdom that can reproduce by the sexual mode of reproduction. Sexual reproduction involves the formation of gametes and their fusion to form the zygote. This zygote leads to the formation of new organism.

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Why is it important to avoid applying too much nitrogen fertilizer?
O A. Too much nitrogen can buffer cells from extremes in pH.
B. Too much nitrogen in surface runoff can poison fish.
C. Too much nitrogen in surface runoff can cause algae to overgrow.
O D. Too much nitrogen can increase the salinity of soil.

Answers

Answer:

too much nitrogen in surface runoff can cause algae to overgrow

Nitrogen fertilizers used in large-scale agriculture could leave a legacy of pollution that would persist for decades in soil and groundwater, scientists in France and Canada warned, which published a study in the National Academy of Sciences magazine, " PNAS ". According to these scientists, the excess of these fertilizers in the environment has been linked to contaminated drinking water and can cause the rapid growth of algae that compromise aquatic ecosystems and coastal marine life.

Explanation:

Brainliest please?

A scientist is studying the effect on human health of bacteria that live in the human intestine. In her study, she found that the bacteria actually help the body’s immune response. To develop scientific consensus about her idea, the scientist should

Answers

Answer: Publish her results in a peer- reviewed journal

Explanation: correct on Edge.

HELP WILL GIVE BRANLIEST!Can all animals regenerate? Explain.

Answers

Answer:

Almost all the animals can heal wounds, but only some can regenerate. One hypothesis is that certain regeneration-specific genes are expressed exclusively in regenerative species and evolutionarily lost in nonregenerative species.

Explanation:

Good luck and have a great day!

Explain why the scientific process is important when learning about diseases

Answers

Answer:

It provides an objective, standardized approach to conducting experiments and, in doing so, improves their results. By using a standardized approach in their investigations, scientists can feel confident that they will stick to the facts.

Explanation:

It provides an objective standardized approach to conducting experiments

Which of the following is an anthropogenic cause of water pollution?

A. Underwater volcanic activity

B. Riverbank sediment flowing into lakes

C. Farming fertilizers washing into lakes

D. Plate tectonics that cause earthquakes

Answers

Farming fertilizers washing into lakes is an anthropogenic cause of water pollution. Therefore, option (C) is correct.

What is anthropogenic cause of water pollution?

According to the theory of anthropogenic climate change, people are primarily responsible for the present climatic shifts via the use of fossil fuels like coal, oil, and natural gas.

There are several sources of water contamination, both natural and man-made. The most frequent anthropogenic sources of water pollution, however, include: Agriculture runoff (which introduces fertilisers, pesticides, insecticides, and herbicides, as well as other pollutants, into bodies of water including lakes, rivers, and ponds). Therefore, option (C) is correct.

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