A number of antiviral drugs act by preventing viral DNA synthesis. These drugs are typically chemically similar to nucleotides with a modification. For example, the drug may contain all relevant components of a nucleotide, including a proper purine or pyrimidine base, but lack the 3' OH group. How would this modification allow this drug to prevent viral DNA synthesis

Answers

Answer 1
The DNA polymerase of the host cell can only add new nucleotides to the 3’ hydroxyl end of the growing DNA strand. When one of these nucleotide analogs which lack a 3’ hydroxyl end is added to the viral DNA strand being copied, the DNA polymerase can no longer continue transcription. These drugs effectively prevent DNA transcription.
Answer 2

This modification allows the drug to prevent viral DNA synthesis by different mechanisms as an enzyme DNA polymerase follows.

What do you mean by DNA synthesis?

DNA synthesis may be defined as the biological process by which a deoxyribonucleic acid (DNA) molecule is created.

The enzyme DNA polymerase adds some of the nucleotide bases to the strand that contains 3'-OH at the end. But when the end part of the strand lacks the 3' OH group, it inhibits the process of DNA transcription.

Therefore, this modification allows the drug to prevent viral DNA synthesis by different mechanisms as an enzyme DNA polymerase follows.

To learn more about Viral DNA synthesis, refer to the link:

https://brainly.com/question/1145964


Related Questions

Your Hot Wheels car travels 120 cm in 1.34 seconds. What is its SPEED?
0.01 cm/s
67.55 cm/s
89.55 cm/s
160.80 cm/s

Answers

Answer:

c) 89.55 cm/s

Explanation:

in this situation you have to divide to find the speed-

120/1.34 = 89.55223880...

closest answer is c

or rounded

89.55

hope this helps.

what are all the zodiac names
if I was born in september what is my zodiac
I WILL GIVE 20 POINTS FOR THIS

Answers

Answer:

Virgo

Explanation:

Have a great day :)

Answer:

libra, cancer, aries, scorpio, leo, pisces, saggitarius, aqurious, capicorn, tarous, and gemini

Explanation:

Virgo

The zodiac sign for September  is Virgo.

This zodiac symbol is considered to influence those born August 23 - September 22, under the Virgo zodiac sign

4. A bacterium is discovered with new mutated form of isocitrate dehydrogenase that catalyzes the same reaction but produces hydrogen gas instead of NADH. a. Write a balanced equation for the new reaction. b. What affect does this mutation have on the amount of ATP produced from one glucose molecule

Answers

Isocitrate + NAD+ -> a-ketoglutarate + CO2 + H2

The amount of ATP produced from one molecule of glucose will decrease because NADH is no longer produced in the isocitrate dehydrogenase reaction. Without generation of this high energy electron carrier there will be less electrons from one molecule of glucose that are transferred to and through the electron transport chain. So there will be less protons (H+ ions) pumped into the intermembrane space. So there will be less of a H+ ion gradient across the inner mitochondrial membrane to drive the synthesis of ATP by ATP synthase.

A bacterium is discovered with a new mutated form of isocitrate dehydrogenase that catalyzes the same reaction but makes H₂; the reactant is isocitrate, and the product is alpha-ketoglutarate. As the proton count decreases, less ATP is produced.

What is the importance of the proton gradient in energy production?

The proton gradient is formed during the electron transfer chain (ETC) by using all the NADH and FADH₂ that are derived from the glycolysis and kreb cycle. NADH and FADH₂, for example, are two compounds that travel through the different complexes to create the proton gradient, which later produces ATP; however, when H₂ is produced instead of NADH, less of a proton gradient is formed, and thus less ATP is produced. The equation is isocitrate+ NAD+ → alpha-ketoglutarate +CO₂ + H+

Hence, the reaction is composed of substrates isocitrate, NAD+, and products alpha-ketoglutarate, CO₂, and a proton (H+), which will be formed with significantly less ATP than the normal ATP produced from the one glucose.

Learn more about the proton gradient here.

https://brainly.com/question/28046848

#SPJ2

constellation are group of stars that from patterns.
True or False

Answers

Answer:

true

Explanation:

id 79465414692 password FxVg9y

some _______ environmental changes can cause tge genes of an entire population to change.​

Answers

Answer:

some unfavorable environmental changes can cause the genes of an entire population to change.​Unfavorable

Explanation:

¿Qué organismo se nutren a través de la fotosíntesis?

Answers

Las celulas vegetales es decir las plantas

I need help please!!!

Answers

Answer:

I believe the answer is x

Explanation:

I can't really tell from the graph bit I hope this helps

Its x I think. Baiiiiiiiiiiiii

Please Help
Which resource is renewable?
A. Wind
B. Diamonds
C. Aluminum
D. Coal

Answers

Answer:

A. Wind

wind is a renewable resource because there is unlimited supply of it.

Explanation:

Reread the first and second paragraphs. Number the events below in order from first to last.
___ Local business owners and movie studios began working together to bring films to local theaters.
___ Early movie theaters started opening in the early 1900s.
___ The first movies were made in the late 1800s.

Answers

Movies made in 1800s
Movie theaters open in the 1900s
Business owners team up

Which of these statements about Hox genes is true?
A. They regulate the development of body parts.
B. They occur in random places on the chromosome.
c. They were first discovered in mammals.
D. They are only involved in the development of embryos,
not adults.

Answers

Answer:

A. They regulate the development of body parts

Explanation:

I just did it on Savvas (Pearson)

The statement which is true about HOX genes is they regulate the development of body parts.

What do you mean by HOX genes?

HOX genes may be defined as components of the homeotic transcription factor family that play a key part in controlling the body plan.

HOX genes play two important roles, which are given below:

Specifying the place where the limb of organisms forms.Specifying whether the particular mesenchyme cells will become stylopod, zeugopod, and autopod.

Therefore, the statement which is true about HOX genes is they regulate the development of body parts.

To learn more about HOX genes, refer to the link:

https://brainly.com/question/22998796

#SPJ2

Please match the following terms with the appropriate definitions.
Distance

[ Choose ]
Displacement

[ Choose ]
Slope

[ Choose ]
SI unit for speed and velocity

[ Choose ]
SI unit for acceleration

[ Choose ]

Answers

Distance - an amount of space between two things

Displacement - something that is moved from original place or the area between a object when place in water (volume)

Slope - rise over run or an angle of a line

Sl unit for speed and velocity - meter per second

Sl unit for acceleration - meter per second squared

7 examples of RNA and DNA ​

Answers


Rotavirus, polio virus, yellow fever virus, dengue virus, hepatitis C virus, measles virus, rabies virus, influenza virus and Ebola virus are examples of RNA virus.

Adenovirus, herpes virus, poxvirus and papillomavirus are examples of DNA virus.

From his observations in the oceanic islands like the Galapagos, Darwin felt that: isolation is a significant factor in adaptation and speciation spontaneous generation is a significant factor in adaptation and speciation volcanic soils are a significatnt factor in adaptation and speciation inheritance of acquired characteristics is a significant factor in adaptation and speciation. none of these is correct

Answers

Answer:

isolation is a significant factor in adaptation and speciation

Explanation:

In the theory of evolution by natural selection proposed by Darwin, adaptation refers to the adjustment of organisms to their environments in order to increase their chances of survival in that environment. In the Galapagos Islands, Darwin observed that finches had different types of beaks adapted to the type of food they ate. From this observation, Darwin proposed that finches evolved to eat different food sources. In this case, the islands lead to an adjustment (evolutionary) process by which geographically isolated individuals accumulate genetic differences in order to adapt them to the environmental conditions in the islands, which then may also prevent breeding between individuals from different islands when they are reunited (i.e., it may also lead to speciation).

Help me lable cells pls? Prokaryote and Eukaryote?​

Answers

The diagram is not clear but I will only try to answer what I can see

A is the pilus and it help the bacteria to attach itself to a specific surfaces or to other cells
B is the cytoplasm and it protect the cell from damages and also store molecules required for cellular processes
C is the plasma membrane they keep toxic substance out of the cell and regulate the in and out of specific molecule
K is the chloroplast and it store chlorophyll which is responsible for the color pigment
M is the large vacoule, and it stores waste , water and nutrients in the cell

I can’t see L well , that is why am unable to answer it
Thank you

The process of nitrification is
carried out by what group of
organisms?
A. producers
B. animals
C. bacteria

Answers

C) Bacteria is the correct option

How does the movie “The Martian” related to a biology concept?

Answers

Answer:

Because of the garden that the dude made on mars.

Explanation:

The dude grew plants from his crew's poop and made a little tent with airtight seals, and as he said, once you grow something, you colonize it.

Which of these describes a nebula

Answers

Answer:

A nebula is a giant cloud of dust and gas in space. Some nebulae (more than one nebula) come from the gas and dust thrown out by the explosion of a dying star, such as a supernova. Other nebulae are regions where new stars are beginning to form. For this reason, some nebulae are called "star nurseries."

Explanation:

What signals your body to breathe out, or exhale. We learning about the respiratory system

Answers

Answer: Your brain constantly gets signals from your body which detect the amount of oxygen and carbon dioxide in your blood. Your brain will send signals to the muscles involved in breathing and adjust your breathing rate depending on how active you are.

HOPE THIS HELPED HAVE A WONDERFULL DAY!

Which labels correctly complete the diagram

Answers

Answer:

The answer is the first one, i hope it helps

Explanation:

If an object is stationary, it means....

A) There are balanced forces acting on the object

B) There are unbalanced forces acting on the object

C) The object is in motion

D) The object is experiencing air resistance

Answers

The answer should be A.

What are the monomers that determine the shape of a protein?

Answers

Answer:

Chains of amino acids make proteins. They can fold into many different complex shapes.

Most earthquakes happen along the ?
A.fault
B.volcanic mountains
C.pacific ring of fire
D.mid- ocean ridge

Answers

D. Mid- ocean ridge

Two protein kinases, PK1 and PK2, work sequentially in an intracellular signaling pathway. You create cells that contain inactivating mutations in the genes that encode either PK1 or PK2 and find that these cells no longer respond to a particular extracellular signal. You also create cells containing a version of PK1 that is permanently active and find that the cells behave as though they are receiving the signal even when the signal is not present. When you introduce the permanently active version of PK1 into cells that have an inactivating mutation in PK2, you find that these cells also behave as though they are receiving the signal even when no signal is present.
Answer the following question in the space give.
A. From these results, does PK1 activate PK2, or does PK2 activate PK1? Explain your answer.

Answers

Answer:

The answer is "PK1 activates PK2"

Explanation:

All enzymes were required again for the transmission of a signal. If Pk1 is continuously active, pk2 will no longer be required, as per my theory, can trigger pk1, therefore the cells were if they amplify the message even when they're not active. But since both enzymes require regular copies together for transduction, pk2 is simple and pk1 requires to also be activated.

A group of students burned three different kinds of food and
collected data.
Food
sample
Mass
Starting
temp.
Ending
temp.
1
100 g
20°C
24°C
2
50 g
20°C
30°C
3
110 g
20°C
27°C
6a. How many calories were contained in each piece of food? Remember:
cal = m XAT

Answers

Answer:

sample

Mass

Starting

temp.

Question 6
Below which of the following pH is rain regarded as 'acid rain'?
10
6
9
7

Answers

Answer:

10

Explanation:

Why are ferns and mosses poorly adapted to a terrestrial life​

Answers

Answer:

Because they require a WATER medium for reproduction

Explanation:

Ferns are a group of living organisms under the division; Pteridophyta while mosses belong to the group Bryophyta. Mosses are considered primitive and non-vascular plants because they lack true stems, leaves and roots or vascular tissues. while ferns possess these organs, hence, are said to be vascular.

However, ferns and mosses are poorly adapted to a terrestrial life i.e. life on land because they both require a water medium for their motile male gametes to swim and fertilize their eggs (female gametes).

the development of lateral roots is intiated by the the cork or periderm​

Answers

Answer:

Because lateral roots are initiated in the pericycle and grow out through the cortex and epidermis, they are said to have an internal, or endogenous, origin, in contrast to the external, or exogenous, origin of leaves and the apical meristem of stems (see below Stems).

Explanation:

The amount of light, pressure, and temperature are examples of?

Answers

Explanation:

The answer is No. You know light from Stars travel in cold temperature of space and different pressure as they enter our planet after travelling many light year to reach us at the same the speed.

Light bends when entering a different medium(refraction). Even if the medium is same and the temperature is different it will get bend. As the 2 different temperature air behave like 2 mediums (Due to distribution of atoms ).

But light doesn't’ bend by heating or by putting pressure on it.

What is the difference between osmosis and diffusion:)

Answers

Osmosis is the movement of solvent particles
Diffusion is the movement of particles from an area of higher concentration to lower concentration
Osmosis is the movement of water molecules through the cell and Diffusion is the movement of molecules, such as oxygen, in and out of a cell

Which of the following answer choices best describes the image shown above?
Choose 1 answer:
It depicts sexual reproduction occurring through the fusion of gametes, a process that leads to
genetic variation.
It depicts sexual reproduction occurring through parthenogenesis, a process that leads to genetic
variation
It depicts asexual reproduction occurring through binary fission, a process that does not lead to
genetic variation
It depicts asexual reproduction occurring through budding, a process that does not lead to genetic
variation

Answers

Answer:it depicts asexual reproduction occurring through binary fission, a process that does not lead to genetic variation

Explanation:

The choice that best describes the image shown above is it depicts asexual reproduction occurring through binary fission, a process that does not lead to genetic variation. The correct option is C.

What is asexual reproduction?

Asexual reproduction is a mode of reproduction in which only one parent is needed. There are different types of asexual reproduction, like budding, vegetative reproduction, fragmentation, and binary fission.

This reproduction does not require the fusion of sperm and egg. The offspring is exactly identical to the parent. Many organisms reproduce in asexual reproduction, hydra, paramecium, starfish, etc.

Thus, the correct option is C. it depicts asexual reproduction occurring through binary fission, a process that does not lead to genetic variation.

To learn more about asexual reproduction, refer to the link:

https://brainly.com/question/4100787

#SPJ2

Other Questions
Which measure of variability is the most appropriate for this set of values?13, 42, 104, 36, 28, 6, 17A. rangeB. interquartile rangeC. mean absolute deviationD. absolute deviationE. either interquartile range or mean absolute deviation How can you apply this approach to the classification of living things? Keisha works as a tutor for $13 an hour and as a waitress for $9 an hour. This month, she worked a combined total of 101 hours at her two jobs. Let t be the number of hours Keisha worked as a tutor this month. Write an expression for the combined total dollar amount she earned this month. The loudness, L, measured in decibels (Db), of a sound intensity, I, measured in watts per square meter, is defined as L = 10 log StartFraction I Over I 0 EndFraction, where I 0 = 10 Superscript negative 12 and is the least intense sound a human ear can hear. Jessica is listening to soft music at a sound intensity level of 10^-9 on her computer while she does her homework. Braylee is completing her homework while listening to very loud music at a sound intensity level of 10^-3 on her headphones. How many times louder is Braylees music than Jessicas? Name 4 other books authored by S.E. Hinton that were made into movies Determine if the sequence below is arithmetic or geometric and determine the common difference / ratio in simplest form. 4,9,14,... ILL GIVE BRAINLIEST PLZZ I NEED THIS Was leaving her child's health up to faith the same as leaving it up to fate? In the context ofthis story, to what extent can we control our fate? Cite evidence from this text, your ownexperience, and other literature, art, or history in your answer. A purpose of postmortem care is to make the body ready for family viewing.TRUE OR FALSE? What factors influence ocean water density? THIS IS FOR TODAY SOMEONE HELP ME PLS!!!NO LINKS PLEASE PLEASE NO LINKS OR ELSE YOU'LL BE REPORTED! Only answer if you're very good at English.Read the dictionary entry.foolproof (adj): 1 : designed to function despite human error 2 : without possibility of failure Which sentence uses the word foolproof as described by the second definition?A: The defense lawyer concluded his remarks with a foolproof argument of the defendant's Innocence.B: Foolproof methods of transportation may become a reality in the near future.C: The new computers were not foolproof in the hands of untrained users.D: Scientists were certain that despite being out of their control, the probe would be foolproof. According to this diagram, what is cos 16? 25 90 24 OA OB. 24 7 OC. OD. help asap pls need help by 1230 pt thanks Explain Communism, why does communism not really work in real life? 15 points,I will mark brainliest. ILL MARK BRAINLIEST PLEASE HELP!!!What is the solution to the equation612O x= 1O x= 2O x=8O x= 4 find the perimeter of each polygon. Assume that lines which appeared to be tangent are tangent. Which phrase should be used instead of the one below?Grey shows in this quote...A) The phrase has no errors.B) Mark Grey shows in this quote...C) This quote by Mark Grey is a quote...D) In stating this, Grey is pointing out... The following box plot shows the number of years during which 40 schools have participated in an interschool swimming meet:A box and whisker plot is drawn using a number line from 0 to 10 with primary markings and labels at 0, 5, 10. In between two primary markings are 4 secondary markings. The box extends from 1 to 6 on the number line. There is a vertical line at 3.5. The whiskers end at 0 and 8. Above the plot is written Duration of Participation. Below the plot is written Years.At least how many schools have participated for more than 1 year and less than 6 years? (5 points)a4 schoolsb8 schoolsc10 schoolsd20 schools A property that offers a 7.5 percent return on the listing price has a monthly net of $810.The property is listed at